Common drugs used to treat ulcers and heartburn can pose a problem for people taking the blood thinner Plavix.
Nexium, Prevacid, Prilosec and Protonix, known as proton pump inhibitors, are enormously popular. But they can be dangerous in heart patients taking the anti-clotting medication.
The proton pump inhibitors interfere with Plavix's effectiveness, boosting the risk of heart and stroke by 50 percent in patients taking both drugs.
Los Angeles Times May 7, 2009