Grilling this weekend? Some spices may play role in reduced cancer risk

Researchers report that adding certain spices to your burgers before tossing them on the grill this summer will not only add to the flavor of the meat, but they can also cut the risk of cancer long associated with the cooking of beef.
Scientists at Kansas State University found that three spices in particular — fingerroot, rosemary and tumeric — seem to direct the greatest amount of antioxidant activity toward preventing the formation of heterocyclic amines (HCAs). HCAs, they note, are the cancer-causing compounds that are produced when foods such as beef are barbecued, grilled, broiled or fried.

Specifically, the three spices appeared to cut back on HCA production by upwards of 40%, the team observed, thereby significantly reducing the HCA-associated risk for developing colorectal, stomach, lung, pancreatic, mammary and prostate cancers.

"Cooked beef tends to develop more HCAs than other kinds of cooked meats such as pork and chicken," KSU food chemistry professor J. Scott Smith noted in a news release. "Cooked beef patties appear to be the cooked meat with the highest mutagenic activity and may be the most important source of HCAs in the human diet."

Therefore Smith and his colleagues looked into the HCA-inhibiting potential of six spices: cumin, coriander seeds, galangal, fingerroot, rosemary and tumeric.

Of all those investigated, rosemary came out on top as the strongest protector against HCA.

The authors suggested that consumers integrate these spices into their menus when appropriate, noting that some, such as rosemary, come in an extract form that has demonstrated HCA inhibition of 61% to 79%.

They pointed out that spicing allows for the sort of high-temperature cooking (above 352 degrees Farenheit) that is typically recommended for safe grilling, while at the same time blocking the increased HCA production that is known to occur when the flames intensify.

Smith and his team plan further research to see what other marinades and powders might do by way of HCA curtailment — they noted that earlier work has shown that marinating steaks with particular herbs and spices effectively lowers HCA production.

A little chocolate might help cut cholesterol

But chocolate lovers shouldn't take the news as license to indulge. Chocolate only helped people who already had risk factors for heart disease, and only when consumed in modest amounts, Dr. Rutai Hui of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing and colleagues found.

Several studies have suggested that chocolate may be good for you. One study released in March showed that among 19,300 people, those who ate the most chocolate had lower blood pressure and were less likely to suffer a stroke or heart attack over the next 10 years. But like the new analysis, that research came with caveats; the difference in chocolate consumption between the top and bottom chocolate-consuming groups was around 6 grams, or about one-seventh of a Hershey's milk chocolate bar.

In the new analysis, Hui and colleagues searched the medical literature to find studies that looked at how cocoa affected blood fats, or lipids, and found eight trials including 215 people. When all studies were analyzed together, the researchers found eating cocoa cut levels of LDL, or "bad" cholesterol, by about 6 mg/dL and reduced total cholesterol by the same amount. But cocoa had no effect on cholesterol in the three highest-quality studies.

Further analysis showed that only people who ate small amounts of cocoa, an amount containing 260 milligrams of polyphenols or less, experienced cholesterol lowering effects; people who consumed more showed no effect.

Polyphenols are antioxidant compounds found in fruits, vegetables, chocolate and red wine. A 1.25-ounce bar of milk chocolate contains about 300 milligrams of polyphenols.

The researchers also found that healthy people didn't get any cholesterol-lowering benefits from cocoa, but people with risk factors for heart disease, such as diabetes, saw their LDL cholesterol and total cholesterol drop by around 8 mg/dL each.

Eating moderate amounts of cocoa could be "a worthwhile dietary approach" for preventing high cholesterol in certain groups of people, Hui and colleagues conclude in a report in the American Journal of Clinical Nutrition.

"Future research efforts," they say, "should concentrate on higher-quality and more rigorous randomized trials with longer follow-ups to resolve the uncertainty regarding the clinical effectiveness. Then we can really eat chocolate without feeling guilty."

Rheumatoid arthritis 'on the rise in women'

One of the most common forms of arthritis is on the rise among women in the US, according to a study.

Researchers from the Mayo Clinic in Minnesota say rheumatoid arthritis cases rose 2.5% between 1995 and 2007, after 40 years of decline, but fell among men in the same 12-year period,

Rheumatoid arthritis affects around 350,000 people in the UK.

The condition is a form of arthritis which happens when the body's immune system attacks joints.

This causes pain and swelling, which can lead to problems with mobility.

It often starts between 40 and 50 years of age and women are three times more likely to be affected by the condition than men.

The study looked at cases of rheumatoid arthritis in Minnesota between 1995 and 2007.

They examined the medical records of 1,761 residents in Olmsted County.

They found cases of rheumatoid arthritis increased by 2.5% per year from 1995 to 2007, while it fell in men by 0.5%.

Study leader Dr Sherine Gabriel said: "We observed a modest increase of rheumatoid arthritis incidence in women during the study period, which followed a sharp decline in incidence during the previous four decades."

Previous studies have found a link between cigarette smoking and rheumatoid arthritis.

Vitamin D deficiency has also been associated with the development of the condition.

Commenting on the work, published in the journal Arthritis and Rheumatism, Ailsa Bosworth, Chief Executive of UK charity the National Rheumatoid Arthritis Society, said the findings were a concern.

She said: "I would like to assure people living with rheumatoid arthritis that in the last 10 years due in part to the use of biological therapies and tighter control of the disease at an earlier stage that more and more people with this long-term condition are managing to stay working and live very full productive lives.

"However more definitely needs to be done to raise public awareness of rheumatoid arthritis and that people raise their risk of developing the disease if they smoke."

Fewer sugary drinks may lower blood pressure: study

They found overweight people with high blood pressure who drank one less sugar-laden beverage a day significantly lowered their blood pressure over 18 months.

For most Americans this means cutting soft drink intake in half.

"We found if you lower your consumption of sugary drinks, it may help you reduce your blood pressure," said Dr. Liwei Chen of Louisiana State University Health Science Center, whose findings appear in the journal Circulation.

"If you reduce your consumption by two servings, you would probably lower your blood pressure even more," Chen said in a telephone interview.

The study adds to mounting pressure on U.S. food and beverage companies as newly passed health reform legislation shifts the nation's focus on ways to prevent disease as well as treat it.


Too much sugar not only makes people fatter, but is also a key culprit in diabetes, heart disease and stroke, according to the American Heart Association.

Several states, including New York and California, have weighed a tax on sweetened soft drinks to defray the cost of treating obesity-related diseases.

A report by the U.S. Institute of Medicine in February declared high blood pressure a "neglected disease" in the United States, accounting for one in six deaths and adding $73 billion a year in health costs.

Chen's study looked specifically at the effect of sugar intake on blood pressure. The team used data on 810 adults aged 25 to 79 with borderline high blood pressure -- readings of 120/80 to 139/89 -- and stage I hypertension -- readings of 140/90 and 159/99

At the start of the study, people drank 10.5 ounces (310 ml), or roughly one serving, of sweetened beverages a day. They included drinks sweetened with sugar or high-fructose corn syrup such as soft drinks, fruit drinks and lemonade.

After 18 months, average consumption had fallen by half a serving, and both the systolic blood pressure -- the "top number" blood pressure reading when the heart beats -- and diastolic blood pressure -- the "bottom number" reading between beats -- had fallen significantly.

They said drinking one less soft drink a day resulted in a 1.8 millimeters of mercury drop in systolic pressure and cut diastolic pressure by 1.1 millimeters of mercury.

"Weight loss is part of the reason but not all," Chen said, noting that even after controlling for that, the improvement in blood pressure was statistically significant.

She said American adults drink an average of 2.3 servings (28 ounces/828 ml) of sugar-sweetened beverages per day.

The American Beverage Association says sugar-sweetened drinks do not pose any particular health risk, and are not a unique risk factor for obesity or heart disease.

Vitamin E may protect lungs

People who take vitamin E supplements regularly for years -- whether they are smokers or nonsmokers -- may lower their risk of chronic obstructive pulmonary disease, the lung condition that is the fourth leading cause of death in the United States.

COPD includes emphysema and chronic bronchitis and is often, but not always, caused by smoking.

While the risk reduction is relatively small, 10 percent, COPD is a common and life-threatening condition in which a decline in lung function can be slowed down but not reversed. COPD symptoms include shortness of breath, coughing, and fatigue.

"The effect appears to be modest. But for something for which there isn't really any effective therapy and tends to be a degenerative condition, anything that would reduce the risk even somewhat is not an insubstantial benefit," says Jeffrey B. Blumberg, Ph.D., a professor of nutrition at Tufts University in Boston who was not involved in the study.

Exercise may keep cancer patients healthier during, after treatment

CHICAGO – Breast and prostate cancer patients who regularly exercise during and after cancer treatment report having a better quality of life and being less fatigued, according to researchers at Henry Ford Hospital in Detroit.

"Using exercise as an approach to cancer care has the potential to benefit patients both physically and psychologically, as well as mitigate treatment side effects," says study lead author Eleanor M. Walker, M.D., division director of breast services in the Department of Radiation Oncology at Henry Ford Hospital.

"Plus, exercise is a great alternative to patients combating fatigue and nausea who are considering using supplements which may interfere with medications and chemotherapy they're taking during cancer treatment."

Dr. Walker will present a poster with the study's design and intervention methods June 7 at the 2010 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. The abstract is now available online at www.ASCO.org.

To study how exercise impacts cancer patients, Dr. Walker and her colleagues at Henry Ford's Josephine Ford Cancer Center and the Henry Ford Heart & Vascular Institute developed a unique program called ExCITE (Exercise and Cancer Integrative Therapies and Education).

ExCITE works with patients who are receiving cancer treatment to create individualized exercise programs. Some patients come into one of Henry Ford's fitness centers to workout, while others have plans that allow them to exercise at home during various stages of their care.

The study group thus far includes 30 female breast cancer patients and 20 prostate cancer patients, all ranging in age from 35 to 80. All were newly diagnosed when they began ExCITE. The study followed the patients during treatment and for one-year following completion of cancer treatment.

Before beginning the exercise program, Henry Ford's Preventative Cardiology Division measured the patients' exercise capacity, skeletal muscle strength and endurance. General blood work, metabolic screens, bone density and inflammatory biomarkers also were obtained at the start of the program.

Exercise and diet recommendation for each patient were based on their baseline exercise tolerances, weight, overall health, and type of cancer treatment they would receive. Acupuncture was used for patients who experienced hot flashes, pain, nausea/vomiting, insomnia and neuropathy as the result of cancer treatment.

Cheryl Fallen of Gross Pointe Park, Mich., was undergoing chemotherapy for breast cancer while she took part in the ExCITE program. Through a mix of exercise, acupuncture and good nutrition, she didn't experiencing some of the more common side-effects from treatment – nausea, fatigue and trouble with memory.

"ExCITE offers cancer patients a way to holistically approach their cancer care by tailoring a specific exercise routine to fit the needs of the patient, whether it's rehabilitation after surgery, or to enhance circulation or improve the immune system prior to chemotherapy or radiation," says Fallen.

When her white blood cell count fell during chemotherapy, Fallen would work out at home using an exercise band or by walking outdoors. When she was well enough to return to the gym, her workouts consisted of using the exercise ball and treadmill, and doing other strength-training exercises.

"Overall, the program makes you feel better about yourself. It's a positive support for cancer patients, and I really think it's allowed me to be more productive during my treatment," says Fallen.

Study of the ExCITE program is ongoing, with Dr. Walker and her colleagues continuing to investigate the potential benefits of exercise for cancer patients.

Ginger May Ease Muscle Pain

Ginger root has been used as a folk remedy. Now researchers have found evidence that daily ginger consumption reduces muscle pain caused by exercise.

The study, which will be published in the September issue of the Journal of Pain, was funded by the McCormick Science Institute — yes, an offshoot of the company that makes and sells spices.

While ginger had been shown to exert anti-inflammatory effects in rodents, its effect on experimentally-induced human muscle pain was largely unexplored, said University of Georgia researcher Patrick O'Connor. It was also believed that heating ginger, as occurs with cooking, might increase its pain-relieving effects.

O'Connor directed two studies examining the effects of 11 days of raw and heat-treated ginger supplementation on muscle pain.

Participants in the studies, 34 and 40 volunteers, respectively, consumed capsules containing two grams of either raw or heat-treated ginger or a placebo for 11 consecutive days. On the eighth day they performed 18 extensions of the elbow flexors with a heavy weight to induce moderate muscle injury to the arm. Arm function, inflammation, pain and a biochemical involved in pain were assessed prior to and for three days after exercise.

The studies showed that daily ginger supplementation reduced the exercise-induced pain by 25 percent, and the effect was not enhanced by heat-treating the ginger.

The study involved a small number of individuals, however, and further study would be needed to confirm the results.

"The economic and personal costs of pain are extremely high," O'Connor said. "Muscle pain generally is one of the most common types of pain and eccentric exercise-induced muscle pain specifically is a common type of injury related to sports and/or recreation (e.g., gardening). Anything that can truly relieve this type of pain will be greatly welcomed by the many people who are experiencing it."

Study suggests processed meat a real health risk

Eating unprocessed beef, pork or lamb appeared not to raise risks of heart attacks and diabetes, they said, suggesting that salt and chemical preservatives may be the real cause of these two health problems associated with eating meat.

The study, an analysis of other research called a meta-analysis, did not look at high blood pressure or cancer, which are also linked with high meat consumption.

"To lower risk of heart attacks and diabetes, people should consider which types of meats they are eating," said Renata Micha of the Harvard School of Public Health, whose study appears in the journal Circulation.

"Processed meats such as bacon, salami, sausages, hot dogs and processed deli meats may be the most important to avoid," Micha said in a statement.

Based on her findings, she said people who eat one serving per week or less of processed meats have less of a risk.

The American Meat Institute objected to the findings, saying it was only one study and that it stands in contrast to other studies and the U.S. Dietary Guidelines for Americans.

"At best, this hypothesis merits further study. It is certainly no reason for dietary changes," James Hodges, president of the American Meat Institute, said in a statement.

Most dietary guidelines recommend eating less meat. Individual studies looking at relationships between eating meat and cardiovascular diseases and diabetes have had mixed results.

But studies rarely look for differences in risk between processed and unprocessed red meats, Micha said.

She and colleagues did a systematic review of nearly 1,600 studies from around the world looking for evidence of a link between eating processed and unprocessed red meat and the risk of heart disease and diabetes.

They defined processed meat as any meat preserved by smoking, curing or salting, or with the addition of chemical preservatives. Meats in this category included bacon, salami, sausages, hot dogs or processed deli or luncheon meats.

Unprocessed red meat included beef, lamb or pork but not poultry.

They found that on average, each 1.8 oz (50 grams) daily serving of processed meat a day -- one to two slices of deli meats or one hot dog -- was associated with a 42 percent higher risk of heart disease and a 19 percent higher risk of developing diabetes.

They found no higher heart or diabetes risk in people who ate only unprocessed red meats.

The team adjusted for a number of factors, including how much meat people ate. They said lifestyle factors were similar between those who ate processed and unprocessed meats.

"When we looked at average nutrients in unprocessed red and processed meats eaten in the United States, we found that they contained similar average amounts of saturated fat and cholesterol," Micha said.

"In contrast, processed meats contained, on average, four times more sodium and 50 percent more nitrate preservatives," Micha added.

Last month, the Institute of Medicine urged the U.S. Food and Drug Administration to regulate the amount of salt added to foods to help Americans cut their high sodium intake.

The FDA has not yet said whether it will regulate salt in foods, but it is looking at the issue.

Treating Neuromuscular Scoliosis with Chiropractics

Scoliosis іѕ thе kind οf ailment affecting thе spine thаt саn bе seen wіth thе naked eye. Referring tο аn aberrant curvature οf thе connected vertebrae, thіѕ condition mау present еіthеr bесаυѕе thеrе іѕ another condition whісh іѕ already affecting thе muscles οr bесаυѕе іt іѕ a birth defect. Sadly, scoliosis іѕ nοt thе kind οf condition thаt саn bе treated solely wіth chiropractic care, bυt instead іt іѕ a study іn trυе interdisciplinary cooperation.

Generally speaking, thе first indication thаt scoliosis іѕ apparent obviously comes wіth a curved spine. Thе curve mіɡht ɡο еіthеr tο thе left οr thе rіɡht, bυt іt іѕ painfully obvious. IntеrеѕtіnɡƖу, thіѕ condition іѕ nοt always a birth disorder bυt mау bе dormant until a later time, such аѕ adolescence, аt whісh point a sudden appearance οf a hump mау indicate thе problems thе spine іѕ experiencing. Adding tο thіѕ diagnosis іѕ thе fact thаt suddenly hips аnԁ shoulders аrе nο longer even bυt mау bе lacking symmetry.

At thіѕ time a physician іѕ usually sought out fοr hеƖр. WhіƖе ѕοmе patients wіƖƖ first ɡο tο a chiropractor, thе latter wіƖƖ generally emphasize thе need fοr another medical professional tο аƖѕο mаkе a diagnosis ѕіnсе oftentimes surgery іѕ necessitated bу thе presentation οf thе scoliosis. Whеn thе consultation wіth thе chiropractor occurs аftеr a diagnosis іѕ mаԁе bу a medical doctor, thе reason іѕ usually two-fold: thе goal іѕ еіthеr tο avoid surgery οr tο support thе surgeries thаt hаνе already occurred аnԁ thе medications thаt hаνе bееn prescribed. WhіƖе thе former generally speaking іѕ аn unlikely though nοt impossible scenario, thе latter іѕ a wise ԁесіѕіοn οn thе раrt οf thе patient.

Thе chiropractor wіƖƖ appreciate having access tο уουr x-rays simply tο confirm thе exact location οf thе problem. Additionally, аnу surgical procedures performed ѕhουƖԁ bе amply documented, preferably wіth a prognosis fοr results аnԁ a summary οf results actually obtained, аnԁ аƖѕο аn exact summary οf thе medications prescribed, thе frequency οf injections, аnԁ thе outlook fοr progression. Sadly, іn younger patients progression іѕ much more ƖіkеƖу thаn іn adult onset cases, уеt each case revolves οn іtѕ οwn facts аnԁ thеrе іѕ nο guarantee οf stemming thе effects οf scoliosis.

Quite οftеn chiropractors report thаt thеу hаνе ɡrеаt success whеn treating neuromuscular scoliosis, аnԁ іn addition tο mild manipulation thе stress іѕ рυt οn weight bearing exercises whісh аƖѕο focus οn maintaining аnԁ perhaps even increasing thе ability οf thе spine tο mονе. Thе goal іѕ tο avoid аn occurrence οf a slip whісh mау actually lead tο a decrease οf thе range οf motion instead οf аn increase. WhіƖе іt іѕ rare thаt thіѕ happens, іt іѕ a very real danger іf thе exercise regimen іѕ nοt strictly followed аnԁ thе patients spine іѕ permitted tο remain idle аnԁ without proper strength training. Thеrе аrе actually times whеn a chiropractor wіƖƖ suggest thе υѕе οf light muscle stimulation wіth thе hеƖр οf a low electric charge, уеt thіѕ іѕ rarely recommended without thе chiropractor аnԁ physician first communicating аbουt thе long term outlook аnԁ short term goal setting.

Vigorous exercise strengthens hip bones in young children

Researchers from Southhampton and Cambridge Universities in the UK have presented evidence that vigorous physical activity in young children results in stronger hip bones. The results were presented at the World Congress on Osteoporosis (IOF WCO-ECCEO10) in Florence, Italy.

More than 200 six-year olds participated in the study. Using advanced scanning technology, the researchers measured bone mass and analysed the structure of the femoral neck (hip) and thigh bone. Physical activity was assessed for seven continuous days.

The results showed that there was a relationship between time spent in vigorous activity and strength of the femoral neck, both in terms of shape and volumetric mineral density. This was independent of other factors such as diet, lifestyle and physical size.

This supports the argument that increasing physical activity in childhood is likely to improve childhood skeletal bone development, and is thus a potentially important public health strategy towards prevention of osteoporosis in later life.